Lilith, the daughter of Mephisto, is central to Diablo IV's story.
Lilith is an ancient demon and the daughter of Mephisto, one of the three Prime Evils. In Diablo IV, she returns to Sanctuary through a ritual and seeks to shape humanity into a force capable of surviving the conflict between Heaven and Hell.
The campaign follows the player's efforts to understand her return, oppose her followers, and confront the consequences of her influence. Lilith's history also connects to the creation of Sanctuary and to the origin of the nephalem through her relationship with the angel Inarius.
She should not be confused with Andariel, a lesser evil encountered in earlier Diablo games, or with Adria, the witch from the first Diablo. Leah is a human character from Diablo III.