Constantinople is Ezio Auditore's main setting in Assassin's Creed Revelations.
The game is set primarily in Constantinople during the early 16th century, when the city was the capital of the Ottoman Empire. Ezio travels there while searching for Altaïr Ibn-La'Ahad's keys, which unlock a sealed library in Masyaf.
The city is divided into districts associated with areas such as Galata, Constantine, Bayezid, and Imperial. Ezio works with local Assassins and becomes involved in political struggles surrounding Sultan Bayezid II and his sons.
Constantinople is the historic name commonly used in the game's setting; the city is now called Istanbul. Venice belongs mainly to Assassin's Creed II, while Alexandria is strongly associated with Assassin's Creed Origins, so those locations are frequent series mix-ups.