Cristina Yang appeared in 220 episodes of Grey’s Anatomy.
Cristina, played by Sandra Oh, was part of Grey’s Anatomy from its 2005 premiere through the Season 10 finale in 2014. Across that run, she appeared in 220 episodes, making her one of the show’s most prominent original characters. Her final appearance is in “Fear (Of the Unknown),” the 220th episode overall.
That episode follows Cristina as she prepares to leave Seattle for Zurich, where she will take over a medical research institute. Her departure closes a decade-long character arc that includes her surgical training, relationships with Preston Burke and Owen Hunt, marriage to Owen, and exceptionally close friendship with Meredith Grey.
The number is easy to misread because 220 is also the overall episode number of Cristina’s final episode. In this case, the two figures align: Cristina’s last appearance came in the show’s 220th episode. She appears throughout the first ten seasons, although not every episode is centered on her story. Sandra Oh’s exit was widely treated as the departure of one of the original series leads.