Hugh Laurie won the 2006 Golden Globe for Best Actor in a Television Series—Drama for House M.D.
The 63rd Golden Globe Awards honored television and film released during the preceding awards period. Laurie won for his portrayal of Gregory House, the diagnostician whose intelligence, pain, and abrasive behavior drive the series.
This was Laurie's first Golden Globe win for the role, and he won the same category again at the 64th Golden Globe Awards in 2007. The awards helped establish House M.D. as an internationally prominent television drama.
The category concerns the actor's performance, not the series winning Best Television Series—Drama. It is also separate from the Primetime Emmy Awards, where Laurie received multiple acting nominations for House.