Anheuser-Busch Brewery had its headquarters in which U.S. city?

Anheuser-Busch Brewery had its headquarters in St. Louis, Missouri.

The company’s roots in St. Louis stretch back to 1852, when German American brewer George Schneider established the Bavarian Brewery. Eberhard Anheuser later acquired the business, and his son-in-law Adolphus Busch helped transform it into the Anheuser-Busch brewing empire. The historic brewery complex in the city’s Soulard neighborhood became one of St. Louis’s defining landmarks.

Anheuser-Busch introduced Budweiser nationally in 1876 and expanded through innovations such as pasteurization, refrigeration, and refrigerated rail transport. These methods helped the company distribute lager far beyond its local market while maintaining consistent quality.

The company was acquired by Belgium-based InBev in 2008, creating AB InBev. That parent company is headquartered in Leuven, Belgium, which can cause confusion. The trivia answer refers to Anheuser-Busch, the American brewing company and its historic corporate base—not the later multinational parent. St. Louis remains closely associated with the brand and its flagship brewery.